pathology-2018-keynote

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Research & Reviews: Journal of Medical and Health Sciences
ISSN: 2319-9865
October 08-09, 2018
Edinburgh, Scotland
Pathology 2018
Page 24
17th International Conference on
Pathology & Cancer
Epidemiology
Significant progress has been made in characterizing the
genomic landscape of human cancers, directly translating
these approaches into clinical practice. With treatments
increasingly targeted towards specific genetic anomalies in
individual tumors, next generation sequencing (NGS) technology
is becoming a main stay of the cancer diagnostics laboratory,
providing therapeutic options for an individual patient. Multiple
clinical diagnostic assays are now being routinely performed
on a variety of NGS platforms, spanning from single-gene or
multi-gene targeted sequencing to whole genome sequencing.
Furthermore, identification of tumor-specific antigens through
whole-exome sequencing has facilitated a revolution in the
field of cancer immunotherapy. In this presentation, we will
discuss recent progress and clinical application of genomic
characterization of clinical specimens, including blood and urine
samples (liquid biopsies). We will also discuss the genomic and
protein biomarkers that can predict which patients are most
likely to benefit from immune check point inhibition.
Biography
Liang Cheng is the inaugural Virgil H. Moon endowed Professor of Pathol-
ogy and Urology at Indiana University School of Medicine, Indianapolis,
Indiana, USA. Currently, he is the Director of Molecular Diagnostics and
Molecular Pathology Laboratories, Chief of the Genitourinary Pathology
Service, Director of the Urologic Pathology Fellowship. He is Board Certi-
fied in Molecular Genetic Pathology, Anatomic and Clinical Pathology by
the American Board of Pathology. He has received numerous prestigious
awards including the Stowell-Orbison Award from the United States and
Canadian Academy of Pathology (USCAP) and the KossMedal Award from
the International Society of Urological Pathology (ISUP). He received the
Arthur Purdy Stout Prize from the Arthur Purdy Stout Society of Surgical
Pathologists in recognition of outstanding contributions to the field of sur-
gical pathology for a surgical pathologist who is below 45 years old. He
has published over 850 peer-reviewed SCI articles in high-impact scientific
journals. His published work has been cited more than 36,000 times (ISI
Web of Science h-index:98). He authored over 100 book chapters and sev-
eral books. Currently, he is an active member of over 30 Editorial Boards.
He is Editor-in-Chief of “Expert Review of Precision Medicine and Drug De-
velopment”. His research focuses on translational studies of genitourinary
cancers and molecular diagnostics of solid tumors.
Precision cancer diagnostics: new insights,
opportunities and challenges
Liang Cheng
Indiana University School of Medicine, USA
Liang Cheng, RRJMHS 2018
Volume: 7