Case Report Open Access

A Clinical Case Report on Progressive Parkinson’s Disease with Motor and Non-Motor Manifestations

Abstract

Parkinson’s disease (PD) is a chronic, progressive neurodegenerative disorder primarily affecting motor function due to degeneration of dopaminergic neurons in the substantia nigra. It is characterized by hallmark clinical features such as tremor, rigidity, bradykinesia, and postural instability, along with a spectrum of non-motor symptoms. This case report describes a 68-year-old male patient presenting with classical motor symptoms accompanied by cognitive and autonomic disturbances. Clinical diagnosis was established based on neurological examination and response to dopaminergic therapy. The patient was managed with pharmacological treatment and supportive therapies, demonstrating partial symptomatic improvement. This report highlights the importance of early recognition, multidisciplinary management, and the impact of non-motor symptoms on quality of life. Parkinson’s disease remains incurable, but timely intervention can significantly improve patient outcomes.

Emily R. Dawson

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