Adult Respiratory Distress Syndrome: Mechanisms of Lung Injury and Advances in Critical Care Management
Acute Respiratory Distress Syndrome (ARDS) is a severe form of acute lung injury that leads to respiratory failure. First described in 1967, ARDS continues to pose a significant challenge in critical care due to its complex pathophysiology and lack of definitive treatment. The syndrome is characterized by rapid onset of hypoxemia, bilateral pulmonary infiltrates, and decreased lung compliance[1]. ARDS can result from direct lung injuries such as pneumonia, aspiration, and inhalation injury, or indirect causes such as sepsis, trauma, and pancreatitis. The incidence of ARDS varies globally but remains a leading cause of mortality in intensive care units (ICUs). Understanding its mechanisms and improving management strategies are crucial for enhancing patient survival.
Sarah Collins
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