Opinion Article Open Access

Implant-Related Infections: A Persistent Challenge in Modern Clinical Oncology and Surgical Practice

Abstract

Implant-related infections (IRIs) remain one of the most serious complications in modern medicine, particularly in surgical oncology, orthopedics, and cardiovascular interventions. Despite advancements in aseptic techniques, biomaterial engineering, and antimicrobial therapies, infection rates associated with implanted medical devices continue to impose significant clinical, economic, and psychological burdens on patients and healthcare systems. These infections are primarily driven by microbial adhesion, biofilm formation, and increasing antimicrobial resistance, which together make eradication difficult and often necessitate implant removal or revision surgery. This opinion article critically discusses the evolving landscape of implant-related infections, emphasizing their pathophysiology, diagnostic challenges, and emerging preventive and therapeutic strategies. It also highlights the urgent need for interdisciplinary collaboration between clinicians, microbiologists, and biomedical engineers to develop next-generation infection-resistant implants.

Elena V. Petrova

To read the full article Download Full Article