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Phytochemical Analysis of Leaves of Centella Asiatica (L)

Abstract

Centella asiatica (L), commonly known as ‘Indian Pennywort’ belongs to the family Apiaceae (Umbelliferae) have great medicinal values and therefore it is widely use in Ayurvedic medicines. All parts of the plant i.e. leave, stem and root contain numbers of secondary metabolites such as steroids, terpenoids, flavonoids, tannins, glycosides, coumarins, carbohydrates, proteins and amino acids. Because of the richness in phytochemicals, the plant is attributed to possess a number of therapeutic uses such as antimicrobial, anti-inflammatory, astringent, bronchodilator, CNS-depressant, de-toxicant, diuretic, immune stimulant, anticancer and hepato-protective etc. The present study intends to provide an overview of the chemical constituents present in the leaf, stem, and root extract of Centella asiatica(L). Phytochemical screening of Centella asiatica(L) was studied by extracting the dried powder leaves, stem, root with water solvents. The extracts were subjected to qualitative phytochemical analysis using classical method and presence of most of the phytochemicals except steroids, terpenoids, glycosides, protein and amino acid. GC-MS determination of methanol extract of the Centella asiatica(L) leaves to find five phytochemical constitutes have been identified by comparing the chromatogram and peak values of unknown compounds with entries in NIST database. These five phytochemical compounds are Neophytadiene, Eicosanoia Acid, Pentadecanoic acid 14- Bromo, Adipic acid Cyclo hexymethyl ethyl ester and Glycidyl palmitate. The presence of various bioactive compounds confirms the application of Centella asiatica(L) for various treatment.

Keywords

Centella asiatica (L), Phytochemical, Antimicrobial, GC-MS, Steroid

Maya Konwar1,3, Manash Pratim Sarma2, Deep Prakash Parasar2, Devabrata Saikia2, Prasenjit Bhagawati3

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