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Research Article Open Access

Aetiomorphological and Demographic Variations of Post Fever Retinal Complications Following Pathogenic

Abstract

There are several factors that contribute to the development of retinal complications following feverish sickness due to pathogenic infections. However, information on pathogenic-induced feverish sickness trigger retinal complications is fragmentary. Here we undertook this study to analyze the clinical manifestation of febrile syndrome retinal complications following with/without pathogenic infections. A complete ophthalmic examination was performed in 39 patients soon after they diagnosed with acute neuroretinitis, vasculitis, and neurosensory detachment in one or both eyes. Retinal complications were diagnosed based on clinical history. Fundus fluorescein angiography (FFA) showed a solitary or multiple patches of retinitis at the posterior pole and exudation at the macula with serous macular detachment. Early FFA showed hypofluorescence of the lesion, which leads to the hyperfluorescence in the late phase. Optical coherence tomography (OCT) showed inner retinal hyperreflectivity and central macular thickness with foveal detachment and shadowing. Initially, patients were treated with methylprednisolone, followed by oral prednisolone. All patients showed improvement in vision with unilateral cases to an average of 6/12 and bilateral cases to an average of 6/24. Patients also showed resolution of neuroretinitis, macular edema and serous detachment in subsequent follow-up. In summary, post fever retinitis and its related complications with/without pathogenic infections as a condition manifested after onset of fever. Irrespective of the cause of the fever, clinical presentation of patients was similar with inner and outer retinitis at the posterior pole and a favourable response to steroids, suggesting possible remedies against these retinal complications.

G Nageswar Rao, G Prasanna, Huma Rizwan3, Sweta Pal, Silpa Sabnam and Arttatrana Pal

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