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Review Article Open Access

Parvovirus B19: Past, present and future

Abstract

Parvovirus B19 (B19V) is a world-wide distributed virus member of the Parvoviridae family, generae Erythrovirus. It causes a wide list of diseases whose pathological mechanisms are majorly unknown. Many theories have emerged in an attempt to explain the pathogenics of B19V in each of its target organs, most interestingly in bone marrow, myocardium, and endothelium. Persistent infection in these organs allows the virus to infect cells despite presence of adequate antibodies formation. Developings from all over the world report that B19V is encountered in an ever changing manner variety of clinical entities. This new understanding opens the doors to future developments amid of a yet to be discover pathogenesis.

Alfaro C Bassols AC, De la Cabada FJ, De la Cabada JB, Rico E, Velazquez Ferrari MA

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