Synthesis, Characterization and Biological Evaluation of Imidazolium Based Ionic Liquids
Room temperature ionic liquids (RTILs), a class of neoteric solvent have attracted increasing interest over recent years as environmentally benign excellent alternatives to organic solvents in homogeneous and biphasic processes. RTILs are also found to display anti-microbial activities being greatly affected by alkyl chain lengths. In the present investigation, certain imidazolium based ionic liquids were synthesized and the structures were confirmed by elemental and spectral studies such as UV-Vis, FT-IR, 1H-NMR and 13C-NMR and they were screened for their anti – microbial activities against Vibrio cholera, Staphylo coccus aureus, Micro coccus luteus and Klebsiella aerogenes at different concentrations. The anti-microbial activity could be summarized as decreasing in the order Vibrio cholera> Micro coccus luteus Klebsiella aerogenes> Staphylo coccus aureus. Among the various ionic liquids, 1, 2-Dibutyl-3-methylimidazoliumbromide (BBMIMBr) was found to be more toxic than others. The anti- microbial activity of all the ionic liquids was observed to be greater at the concentration of 48mg.
K Rajathi and A Rajendran