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A Facile and Expedient Synthesis of Fischer Indole Derivatives Using Double Salt as an Efficient and Recyclable Catalyst.


Nitrogen containing compounds find wide application as structural components in pharmaceuticals and agrochemicals due to their marked biological activities. Among biologically active heterocycles, Indole and its derivatives enjoys wide range of therapeutic and pharmacological properties as anti convulsant, analgesic, sedative anti-depressive,anti-carcinogenic and hypnotic agents. In this study a new series of Novel 3-(3,5-dimethyl-4H-pyrazol-4-ylidene)-1-[(4-methyl phenyl)sulphonyl]-1,3-dihydro-2H-indole-2-one (4) was synthesized. Structure of the title compound was characterized by spectral techniques like FT-IR and 1H NMR.

Ratnesh Das, and Gulzar Khan

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