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Review Article Open Access

A Review on Combinatorial Chemistry


Present review article is the study on the combinatorial chemistry. This study is important when introducing drug molecule in to clinical therapy. Combinatorial chemistry means the systemic and repetitive covalent connection of different molecular entities i.e., with different building blocks. We are studying the principle, design of combinatorial chemistry. We used different approaches for creating chemical libraries and identification of active ingredients with different types and their advantages and disadvantages. Further detailed study deals with methods of combinatorial chemistry in which methods are responsible for formation of new molecule with the huge application of combinatorial chemistry with systemic and repetitive connection by chemical bonding. We also studied the biological activity of newly synthesized molecule against their targets.

Shaikh SM, Nalawade, Shete AS and Doijad RC

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