Review Article Open Access

A Review on Fosfomycine and its Derivatives: New Scale Inhibitors for Oilfield Application

Abstract

Amino methylene-phosphonate is an antibiotic medication use for urinary problems caused by bacterial infection. It works by interfering with bacterial cell wall synthesis. This is a widely use for studies based on scale inhibitors for various oilfield scales. Calcite and Gypsum new molecules are low toxic for test of fosfomycine. Fosfomycin trometamol synthesis from fosfomycin disodium salt and 1,2-dihydroxypropyl fosfonic acid prepare from fosfomycin disodium salt by hydrolysis method. Under the guideline of NACE, effectiveness comparison of commercial oilfield scale inhibitor HPAA and all these chemicals in inhibiting calcite and gypsum scales was assessed. Heidrun oilfield in Norway was used to evaluate the effectiveness of amino methylene-free phosphonate scale inhibitors (Product-1, Product-2, Product-3, and HPAA) in preventing calcite scale formation. This information suggests that the researchers were interested in understanding the performance of these inhibitors in a specific field environment, likely due to the prevalence of calcite scale issues in that region. The newly developed amino methylene-free phosphonate scale inhibitors demonstrated impressive resistance to calcium ions, effectively preventing the formation of both gypsum and calcite scale. All compounds derived from fosfomycin exhibited remarkable tolerance to high calcium concentrations, remaining stable at levels up to 1000 ppm for 24 hours, outperforming HPAA.

Pravinbhai Natubhai Panchal*, Anushree Ujjankar

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