An Updated Review on The Utilization of Various Carriers and Methods to Prepare Solid Dispersions of BCS Classified Drugs
In preparation of formulation, the solubility factor remains a key concern. Now a day, many drugs especially in BCS class II and IV are observed to have less solubility. Among all solubility enhancing techniques practiced in pharmaceutical field, solid dispersions have proved to be most suitable for improving the bioavailability of these chemical entities. During the preparation of solid dispersion, carriers play a vital role in enhancing the dissolution of hydrophobic drugs. This article however reviews various methods and carriers used for the preparation of solid dispersion, with main emphasis on which carriers and methods have been widely used by researchers over the decades, till now.