e-ISSN:2320-1215 p-ISSN: 2322-0112
Clinical Pharmacokinetics: Exploring Drug Movement Through Absorption, Distribution, Biotransformation, and Elimination
Clinical pharmacokinetics is a core area of pharmaceutical science and medicine that investigates the temporal movement of drugs within the human body. It focuses on the four essential processes—absorption, distribution, metabolism, and excretion (ADME)—that determine drug concentration and duration of action. This discipline plays a critical role in optimizing drug dosing, improving therapeutic effectiveness, and reducing the risk of toxicity. This article presents an overview of pharmacokinetic principles, analytical approaches, and clinical applications, with emphasis on individualized therapy, mathematical modeling, and translational research. A strong understanding of pharmacokinetics supports rational prescribing, enhances patient safety, and improves therapeutic success[1].
Kavya N. Iyer
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