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Commentary Open Access

Commentary on Iron Deficiency Anemia


For years, there has been long lasting effects on Central Nervous system. It is the most common single nutrient disorder from infancy to old people. Iron is very essential component required and involves in metabolism of energy, gene regulation, cell organogenesis, transport of oxygen and storage of oxygen in muscle tissue, enzymatic reactions, neurotransmitter and protein synthesis[1-3]. Anemia is the most common blood disorder affecting about a quarter of people globally. Iron-deficiency anemia affects nearly 1 billion [4]. It is more common in females than males among children, during pregnancy and in the elderly. It decreases the ability to work and increases the cost of medical care. The amount of hemoglobin reduced in the blood is referred as decreases the carrying capacity of oxygen to blood. Three main types of anemia 1. Blood loss – GI bleeding, trauma, thalassemia 2. Decrease red blood cell production – iron deficient, lack of vitamin B12 and various co-enzymes. 3. Increase break down of RBC – mutation in genotype of an individual Deficient of micro and trace nutrients, because of poverty and food insecurity lead to cause iron depletion in blood. A recent study estimated that depletion in nutrients remains a cause of 3.1 million deaths of children and chiefly observed in the areas of Africa and Asia.

Navajyothi Chintoju, Prasanthi Konduru, Rajya Lakshmi Kathula, Ravalli Remella

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