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Research Article Open Access

Disciplined Reactions - A Facile One-Flask Synthesis of 2-Substituted-4-m-methoxy -p-hydroxybezylidene-1-phenyl-2-imidazolin-5-ones and its Biological Evaluation.


Condensation reactions of N-acetyl-, N-benzoyl and N-ptolylglycines with vanillin in presence of isothiocyanate gives 2-m-methoxyp- hydroxystyryl-, 2-p-tolyl- and 2-phenyl -4-m-methoxy- phydroxybenzylidene- 1-phenyl-2-imidazolin-5-ones respectively. These compounds were evaluated in vitro for antibacterial activity.

Aditi Taunk, Ravi Pandey and Archana Taunk

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