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Research Article Open Access

Drug utilization Study on Oral Hypertensive Medication Patients and Assessment of Medication Adherence to JNC-8 Guidelines in North Indian Tertiary Care Hospital: A Cross-Sectional Study.


Introduction: Hypertension is a common disease which is also known as elevated blood pressure above the normal, i.e., systolic blood pressure above 130 mm Hg and diastolic blood pressure above 90 mm Hg. Hypertension is one of the highest prevailing diseases worldwide. Patients with hypertension are at higher risk of developing stroke, myocardial infarction renal failure as well as various vascular diseases. Near about 75 million of adults in the United States are diagnosed with hypertension according to American Heart Association. Methodology: A drug utilization review on of hypertensive drugs was commenced to determine and evaluate the different classes of antihypertensive medications with respect to diagnosis and ADR’s. Study was commenced in Guru Gobind Singh Medical College and Hospital, Faridkot. Study was conducted for period of 6 months commencing from October, 2015 to March, 2016 as per inclusion exclusion criteria. The inclusion criteria were set to patients suffering from hypertension. Results and conclusion: During the study period and as per inclusion criteria of the study, 150 patients were enrolled out of whom 83 (55.3%) were male and were 67 (44.7%) female irrespective to heredity. The age of patients ranged from 21-85 years with a higher number of the patients belonging to age group ranging between 51-60 years (38.7%). Most of the hypertensive patients were illiterate 83 (55.3%) and unemployed 140 (93.7%) and duration of the disease was less than 5 years in 51 (34%) patients. Among 150 hypertensive patients, most common symptom was found to be breathlessness in 22 (14.7%) patients. Among the hypertensive class, it was found that diuretics were most prescribed drug followed by CCB’s, ACE Inhibitors, β-Blockers, α-β adrenergic antagonist and Angiotensin II receptor antagonistsp

Amit Sharma, Tanpreet Kaur Badwal Vishal Gupta, Mahendra Singh Rathore, Manik Chhabra and Ankit Gaur.

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