Review Article Open Access

Hydrodynamics Balance System of Herbal Oral Dosage Form for Nausea and Vomiting of Pregnancy

Abstract

This review aims to design, prepare and evaluate the effectiveness of herbal combination dosage to treat the Nausea and Vomiting of Pregnancy (NVP) and improve the wellness of both mother and fetus. Ginger is widely used in treating situations including gastrointestinal symptoms. Hydrodynamic drug delivery system in herbal dosage form to improves the drug bioavailability and synergetic extend efficacy by retained in the stomach for a prolonged gastric retention time and controlling the medicament release by using natural and biodegradable polymers. The design of bilayer tablets with Ginger root extract powder as sustain release part and other layer contains Mint, Vitamin B6 and Fenugreek seed extract. Formulations were evaluated by floating lag time and in vitro drug release method. The drug release from the optimized formulations was extended for a period of 24 hrs.

Akhilesh Kumar Singh,Neeraj Sharma

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