e-ISSN:2320-1215 p-ISSN: 2322-0112

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Review Article Open Access

Review on Selection of Worst Case Product for Cleaning Validation


The main purpose of cleaning validation is to prove the effectiveness and consistency of cleaning in a given pharmaceutical production equipment to prevent cross contamination and adulteration of drug products with other active ingredients like unintended compounds or microbiological contamination leads to prevent several serious problems and also useful in related studies like packaging component cleaning validation. So it is necessary to select the worst case product and validate it, different techniques are used to select the worst case product, solubility, cleanability, potency, probability of batches of the product. MACO calculation.

Ashwini Mahajan

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