e-ISSN: 2319-9849

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Research Article Open Access

Strategic Synthesis of Furoquinoline Alkaloids through Vilsmeier Haack and Oxidative Cyclization Reactions


A vibrant skeleton for the synthesis of importanant furoquinoline alkaloids such as dictamnine 1, robustine 2, fagarine 3, kokusagnine 4, confussameine 5, haplopine 6, evolitrine 7 and skimmianine 8 is reported. The Vilsmeier Haack reaction was utilized to reach the critical intermediate, in moderate yield, whilst an intra-molecular oxidative cyclization, in the presence of oxalic acid, provided the targeted furoquinoline in high yield.

Sathiyamoorthy S, Pitchai P*, Jemima D and Gengan RM

To read the full article Download Full Article | Visit Full Article

Replica watches