e-ISSN: 2319-9849

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Research Article Open Access

Synthesis, Characterization and Biological Studies of Novel 1,3,4-Oxadiazole Derivatives

Abstract

Naphtho[2,1-b]furan-2-carbohydrazide (2) prepared from reaction between ethyl naphtho[2,1-b]furan-2-carboxylate (1) and hydrazine hydrate, then compound (2) on reaction with CS2/KOH gives 5-(naphtho[2,1-b] furan-2-yl)-1,3,4-oxadiazole-2(3H)-thione (3), Which on mannich reaction followed by reaction with benzoic hydrazine gives different N-(1- ((dialkylamino)methyl)-3-(naphtho[2,1-b]furan-2-yl)-5-thioxo-1H-1,2,4- triazol-4(5H)-yl)benzamide (4a-e). With the help of analytical and spectral data, the structure of these compounds were detected. Antibacterial and antifungal activities of the synthesized compounds were studied

Darshansinh AR, Acharya GD and Govindkumar RV

To read the full article Download Full Article | Visit Full Article

https://transplanthair.istanbul
https://hairclinicturkey.co
https://hairclinicistanbul.co
https://besthairtransplant.co
https://hairtransplantistanbul.co