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The in-vitro Antimicrobial and Antioxidant Potential of ethanolic leaf extracts of Anisochiluscarnosus

Abstract

In the present study, the in vitro Antimicrobial and Antioxidant potential of ethanolic extract of Indian habitants Anisochilus carnosus, which is an annual shrub belonging to the family Lamiaceae which is also known as mint family were evaluated. The current study terminated the antibacterial activity of the extract of Anisochilus carnosus against three different bacterial strains Escherichia coli, Pseudomonas aeruginosa and Bacillus subtilis and Antifungal activity against Candida albicans, Aspergilus niger and Trichoderma viridae. Among the bacterial strains Bacillus subtilis showed the maximum zone of inhibition of 15 mm at 800 μg/disc and among the fungal strains Candida albicans showed the maximum zone of inhibition of 9.5 mm at 800 μg/disc. The Antioxidant Potential by radical-scavenging activity of the extracts was measured as decolourizing activity followed by the trapping of the unpaired electron of DPPH. The percentage decrease of 1, 1-diphenyl-2-picryl hydrazyl radical (DPPH) standard solution was recorded maximum for extracts was at a concentration of 400 μg/ml at IC50 of 29.23%. Total phenolic and Total Antioxidant activity contents in the ethanol extract were μg/ml gallic acid equivalents and 100 mg/ml ascorbic acid equivalents respectively. The reducing power increased sharply as concentrations increased. The present study confirmed that the ethanol extract of Anisochilus carnosus leaves is a potential source of natural antioxidants.

N. Kiruthiga and Dr. D. Sathish Sekar

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