Malgorzata Wiszniewska
Stanislaw Staszic University of Applied Sciences, Pila, Poland
ScientificTracks Abstracts: Res Rev Neurosci
Purpose: Essential thrombocythemia (ET) is characterised by an overproduction of platelets in the absence of states, inducing secondary thrombopoiesis. The most common and significant complication of ET is arterial and venous thrombosis. The most serious complication of ET is stroke. Case description: I present a patient with a stroke that started with an unusual symptom - syncope, successfully treated with rt-PA. 3 years after the stroke, the patient is an independent person with cerebellar-stem symptoms. Further long-term treatment is carried out by a haematologist. Comment: Syncope in ET may be the first sign of stroke. To assess brainstem and cerebellar stroke, MRI should be performed. In ET, thrombolytic treatment of ischemic stroke may be a life-saving treatment. Long-term treatment involving a platelet-lowering medication, along with anti-aggregation drugs, is necessary to treat stroke patients with ET. Females with ET who have suffered from a stroke should not use oral contraception. Key words: ischemic stroke, essential thrombocythemia, JAK2 V617F mutation, platelets, risk factors.