+44 7480725689Jovana D. Paunovic
University of Belgrade, Faculty of Medicine, Department of Pathological Physiology, Dr Subotica 9, RS-11129, Belgrade, Serbia
ScientificTracks Abstracts: Res Rev Neurosci
Rapid development of nanotechnology has enabled researchers to develop advanced nanoparticle - based sensing and drug carrier systems with applications in various biological and medical fields. Today, metallic and other nanomaterials are used in radiology, neurology and cancer research. Unfortunately, toxicity of many classes of nanoparticles has not yet been fully investigated and it is one of the main obstacles for future clinical use. In recent years, many authors have stated that some nanoparticles may exhibit significant cytotoxicity under certain experimental conditions. This mainly refers to the possible generation of reactive oxygen species such as hydrogen peroxide, superoxide anion and hydroxyl radical. This way, some metallic nanomaterials can cause DNA damage and induce biochemical pathways leading to programmed cell death. It is possible that in some cases, oxidative stress caused by metallic nanomaterials might lead to substantial neurotoxicity.
Dr. Jovana Paunovic studied Medicine at the University of Belgrade, Serbia and graduated as MD in 2014. Since 2016, she is employed at the University of Belgrade, Faculty of medicine, Department of Pathological Physiology. Her main interests are computational biology, cellular pathophysiology and nanomedicine. She has published original article in numerous prestigious international scientific journals such as Chemico-Biological Interactions (Elsevier) and Microscopy and Microanalysis (Cambridge University Press).
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