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Every Bone Has Its Tone: An Orthodontist’s Perception

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Bone biology is a complex and vastly growing area of study. It brings together the traditional fields of anatomy, histology, physiology and biomechanics with the increasingly complex fields of molecular genetics. For clinicians like us who work with bone, developing a working knowledge on this topic is essential. Biomechanical manipulation of bone is the physiologic basis of orthodontics and facial orthopedics. The biomechanical response to altered function and applied loads depends on the metabolic status of the patient. Thus, this review article describes in detail about bone metabolism, bone in health and disease and its clinical application in orthodontics.