14 / 18
Page 86
conferenceseries
.com
RRJOMS | Volume 5 | Issue 4 | July, 2017
July 27-29, 2017 Vancouver, Canada
10
th
International Conference on
Emerging Materials and Nanotechnology
Res. Rev. J Mat. Sci. 2017
DOI: 10.4172/2321-6212-C1-003
Effect of in addition on structural, optical, electrical and photoconductivity of iso-coordinated
In
x
Sb
20-x
Ag
10
Se
70
(0≤x≤20) chalcogenide films
Rita Sharma
1
, Shaveta Sharma
1
, Praveen Kumar
2
, R Thangaraj
1
and
M Mian
1
1
Guru Nanak Dev University, India
2
DAV University, India
M
any physical properties the chalcogenide systems strongly depends upon the composition and type of impurity added. In
this work, structural and optical properties of thermally evaporated In
x
Sb
20-x
Ag
10
Se
70
(0≤x≤20) chalcogenide films were
studied. Bulk polycrystalline granules were used for the deposition of thin films. XRD studies reveal the amorphous character
of the as-prepared films. FESEM images reveal a change in irregular trend in the morphological structures with composition.
The EDS spectra show the composition of the as-prepared films is in stoichiometric with the bulk samples. Raman Spectroscopy
shows the occurrence of Sb-Se and Sb-Sb bond vibrations for AgSbSe
2
structural units and In-Se bond vibrations in AgInSe
2
structural units. The optical transmittance and reflectance measurements were used to calculate the absorption coefficient
and the indirect optical band gap is found to increases with indium content. The change in film morphology and change in
the concentration of molecular units have been used to discuss optical properties with the increase in indium content. The
electrical properties, by measurements of DC conductivity, intensity dependence of photoconductivity and IV characteristics,
have been studied to give up the valuable information about the transport mechanism of the charge carriers and the type of
charge carriers in In
x
Sb
20-x
Ag
10
Se
70
(0≤x≤20) thin films.
reetasharma2012@gmail.comEvaluating newly formulated osteoprotegerin-chitosan gel: An
in vitro
and
in vivo
study
Soher Nagi Jayash, Najihah Mohd Hashim, Misni Misran
and
N A Baharuddin
University of Malaya, Malaysia
T
he binding of the receptor activator of nuclear factor kappa-B ligand (RANKL) to the receptor activator of nuclear factor
kappa-B (RANK) on pre-osteoclast is essential for osteoclast maturation and activity. Osteoproteogerin (OPG) is a soluble
decoy receptor for RANKL. Its binding to RANK prevents binding of RANKL to RANK and subsequent hinders activation of
osteoclast. Various
in vivo
studies and clinical trials have investigated the systemic use of OPG in treatment of bone diseases.
Chitosan is a cationic polymer derived from chitin. This material has antimicrobial activity, biodegradability, and muco-
adhesive properties, making it an ideal material for biomedical applications. It also promotes cell adhesion, proliferation
and differentiation. It is suggested that the local application of new formulated OPG-chitosan preparation may have similar
osteogenic potential in the bone defect. The objectives of this study are: (i) to formulate of different forms of OPG-chitosan
gels from different molecular weights of water-soluble chitosan (10, 25, 50 kDa), (ii) to evaluate the gels biodegradation, (iii)
to determine amount of OPG protein release from gels and (iv) to evaluate the cytotoxicity of gels by Alamar Blue assay and
scanning electron microscope. (iv) Efficacy of gel on bone regeneration in rabbit. From our studies we conclude that our gels
are (i) non-toxic (ii) biodegradable and (iii) exhibits sustained release property. (iv) OPG-chitosan has a positive effect on bone
formation. Therefore, we have proven that OPG-chitosan gel is evidently viable to be used locally for potential bone defect
application.
soheernaji20@yahoo.com