pathology-2018-scientifictracks

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Pathology 2018 Research & Reviews: Journal of Medical and Health Sciences
ISSN: 2319-9865 Page 29
October 08-09, 2018
Edinburgh, Scotland
17th International Conference on
Pathology & Cancer
Epidemiology
Date of
sampling Animal data Lympho-cytecount / ul
Cell morphology / additional
finding Tentative diagnosis Outcome
Case 1
March 10,
2013 5 year old female 20,064
Marked toxic heterophilia, and sepsis
evident. Increased lysed cells and
count may have been higher
Secondary reactive lymphocytosis
related to infection and sepsis
Animal died a short
time later
Case 2 May 7, 2012 11 month old, sexunknown 15,480 A few reactive forms Unknown -possibly transient
reactive lymphocytosis
No further submis-
sion from this animal.
Case 3 April 23,
2012
2 year old, sex
unknown
24,112
Cells appeared small/intermediate
and somewhat reactive (larger, darker
basophilic cytoplasm with open
coarse chromatin, and sometimes
indented nuclear forms).
June 19,
2012 32,419 Progressively increasing lymphocyto-
sis –and similar morphology.
Potential chronic lymphocytic
leukemia (CLL)
Lost to
follow up
Case 4 July 16, 2012 4 year old, female 13,968 Unknown -possibly transient
reactive lymphocytosis
No follow up submis-
sions.
Case 5 September 7,
2012
6.5 year old, sex
unknown; the
animal appeared
to have minimal
clinical signs or
illness
117,888
50-60% of the lymphoid cells were
large lymphoblasts. Concurrent
heteropenia. No anemia or thrombo-
cytopenia.
Acute lymphoblastic leukemia.
(ALL)
September
21, 2012 184,230
Developing anemia – non-regenera-
tive with continued heteropenia and
thrombocytopenia now seen as well.
Similar lymphocyte morphology.
October 01,
2012 457,920
Progressive anemia – non-regen-
erative with similar lymphocyte
morphology evident.
October 17,
2012 244,880
Stabilizing anemia – non-regenerative
with similar lymphocyte morphology;
although many lysed, fragmented and
apoptotic remnant cells present. Note:
Likely another 100,000 cells could
be added to the lymphocyte count if
these were countable.
November
05, 2012 672,980
Likely another 28,336 cells could
be added to the lymphocyte count
however these were unclassified
cells based on severe pleomorphism.
Persistent non-regenerative anemia.
Persistent fulminating ALL
Clinical condition had
worsened significant-
ly with anorexia and
severe progressive
ataxia. Elected eutha-
nasia on November
6, 2012
Table 1: 5 cases of moderate to marked lymphocytosis in bearded dragons
Biography
Dr Rand Wilson has joined leading veterinary diagnostic laboratory Finn
Pathologists in the newly created role of Head of Clinical Pathology. Dr Wil-
son received a BSc in Wildlife Biology in 1984 and a Doctorate of Veteri-
nary Medicine in 1988 fromColorado State University. He spent the next 20
years practising small animal, exotic and avian medicine and surgery and
undertaking PhD studies in clinical pathology and infectious disease. He
became a member of the Royal College of Veterinary Surgeons in 2008 and
achieved Board Certification in Clinical Pathology in 2008 from the Ameri-
can College of Veterinary Pathologists. Arriving in the UK in 2008, he gained
experience in the veterinary labs sector before taking up his new role at Finn
Pathologists, one of the UK’s leading veterinary diagnostics laboratories in
Harleston, Norfolk.