Dr. Craig Russell

Dr. Craig Russell
Lecturer in Pharmaceutics
School of Life & Health Sciences
Aston University
UK
 

Dr. Craig Russell has always had a strong interest in science and in particular human biology, health and disease and the associated interventions. His undergraduate degree in Human Biology mapped onto this interest and included molecular and cellular biology, biochemistry and physiology modules among others, which would carry relevance in the physiology and pharmacology setting he progressed into. He further developed his knowledge and bolstered his interest in these fields during his PhD. During this period, formulation of oral liquid antihypertensives formed the initial stages of his project; here an understanding of the chemical and physical properties of drug molecules as well as drug action on a molecular level in a physiological setting was essential. In vitro and In vivo characterization of developed formulations utilising cell and rodent based models paved the way for subsequent genomic investigations into intestinal transporter expression profiling using microarray technology and bioinformatics. Cell culture played a key role during a spin off project which he has been developing in parallel with the main path of research which has seen the isolation and characterization of a novel primary cell line aimed at delineation of gustatory sensation.

Dr. Craig Russell intend to further research on oral liquid formulation targeting the paediatric patient segment by taking the research in a direction of his own to further advance in vitro and in vivo drug absorption modelling. The aim is to benefit the drug development pipeline through an innovative application of novel approaches to permeability assays including genomic and metabolomic approaches not currently exploited while at the same time seeking to enhance and advance the technologies and methodologies used in all of these areas on a day to day basis.