Boron Neutron Capture Therapy

Boron Neutron Capture Therapy (BNCT) is the science of radiation that develops as a hopeful tool for cancer treatment, selectively focusing on boron compounds in tumor cells and releasing tumor cells from the epithermal neutron beam. BNCT enables nuclear reaction that occurs when Boron-10, a stable isotope, is heated by low-energy neutrons to produce α (Helium-4) particles and recombinant lithium-7 nuclei. A large number of Boron atoms (10B) must be formed inside or inside neoplastic cells in order for BNCT to function properly, and sufficient number of thermal neutrons must be taken by 10B atoms to maintain 10B (n, α) large lithium-7 reaction. The most unique property of BNCT is that it can include a large dose gradient between tumor cells and normal cells. BNCT combines the basic idea of ​​chemotherapy focus with the suggestion of a localized approach to traditional radiotherapy.