Although several infections are challenging to treat, advances in nanobiotechnology allowed the utilization of nanotechnology,for example, nanovaccines. Nanotechnology vaccines are powerful in enhancing the immunogenicity over a precise antigen, presenting advantages over other adjuvant approaches, such as expanded stability, prolonged release, decreased immunotoxicity, and immunogenic selectivity.Objective: In this review, we introduce recent advances in carbon nanotubes (CNTs)usedinnanovaccines inordertoinduceeitheracarriereffectoranimmunostimulatoryeffect.Results:CNTs have the potential to model the immune system, providing, between another properties, their adjuvant effects, besides having an excellent carrier effect. Several studies concerning CNT-based nanotechnology vaccines revealthat the immunogenicity relatedto thevaccineantigenis increased,dueto theimmunomodulatory andcarriereffects relatedtoCNTs. Also,dueto the CNTspropertiesofbeingabletocarryimmunogenicmolecules,theycanactlikenon-classicalvaccines,whichaimtohaveboth a molecule-carrier effect and an immunogenic effect, a quality not found in vaccines with traditional formulations. Adapting and modifying the physicochemical properties regarding CNTs for usage in vaccines may additionally enlarge their efficacy in inducing a T cell-based immune response, fundamental in imitation of the battle against several infections in immunotherapeutic process.
Visit for more related articles at Research & Reviews: Journal of Social Sciences
Carbon Nanotubes can orchestrate