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Review Article Open Access

A study of Lipid Profile in Hypertension


Hypertension (HTN) is the most widespread disorder in many nations of the world now-a-days. Many people throughout the world have high BP. The estimate of disease statistic is around 1 billion. Generally 7.1 million deaths occur due to hypertension. It is the condition where the force of the blood against the artery walls is too high. The system that regulates the center is Renin–angiotensin system that produces associate degree accelerator proteinase - a proteinase, which is made up of cells that surround capillary vessel afferent arterioles in response to variety of stimuli, as well as reduced urinary organ pressure, decrease in Intravascular volume, exaggerated sympathetic system activity, exaggerated artery stretch, and other effects. Renin acts on angiotensinogen to break off the peptide angiotensin I. This amide is then acted upon by Hypertension -converting accelerator (ACE) to make the eight-amino-acid amide angiotensin II, a potent agent and stimulant of mineral corticoid release from the adrenal glands. Despite the role of proteinase within the regulation of pressure level, it most likely doesn't play a central role within the pathologic process of most primary or essential hypertension; solely 10% patients have high proteinase activity, where as 60% have stable levels and 30% have decreased levels. In the article we would be discussing about the role of lipid content and its effect on hypertension.

Joshita Sabbineni

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