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Review Article Open Access

Hypocholesterolemic and Antioxidant Potentials of Some Plants and Herbs: A Review.


It is now widely accepted that atherosclerosis is a complex multicellular process involving oxidation of cholesterol and the intracellular accumulation of oxidized cholesterol. This accumulation causes a cascade of inflammatory processes, resulting in an unstable atherosclerotic plaque that ultimately bursts, causing myocardial infarction. From ancient times, botanicals have played a major role in the lifestyle of people. The active phytochemicals derived from these herbs and plants have provided protection against atherosclarosis. The association of hyperlipidemia with the development of atherosclerotic lesion has promoted widespread search for plant based compounds which effectively control the lipid profile in the blood and tissues with least or no toxic effect. Around eighty percent of the global population still relies on botanical drugs and herbal medicines have advanced to clinical use in modern times. Based on these findings, present review is written to identify the “Lipid-Lowering and Antioxidants Properties” of commonly used plants and herbs.

Nidhi Sharma, Preeti Sharma, Nakuleshawar Dut Jasuja and Suresh Chand Joshi

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