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Review Article Open Access

Role of Human Papilloma Virus Infection in Cancer of Cervix


Worldwide the Cervical cancer is the second most common type of cancer. This type of cancer that begins in the cervix cells is a sexually transmitted disease. Genital infection having role also in cancer cervix like gonorrhea, herpes simplex virus (type 2) and syphilis. A virus named human papillomavirus (HPV) causes this type of cancer, and it causes transformation in the cervix. The link between HPV infection of the cervix and the cancer is believed one of the significant scientific findings in the last three decades. The transformation zone of the cervix is the most common site in which the cancer is related to it for unknown causes. This transformation zone that is located between different type of epithelium mainly in the oropharynx, cervix and anus has a close relationship to the infection by Human papilloma virus (HPV). Although it is expensive, the primary prevention by the vaccine stills the most effective method for cancer cervix. This vaccine is effective and safe.

Rasmy A, Osama A, Mashiaki M and Amal A

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