ISSN: 2319-9865

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Directly sampled endometrial cytology for screening of endometrial cancers


17th International Conference on Pathology & Cancer Epidemiology

October 08-09, 2018 Edinburgh, Scotland

Yuko Sugiyama and Katsuhiko Hasumi

Cancer Institute Hospital, Tokyo, Japan

Posters & Accepted Abstracts: RRJMHS

Abstract

Objective: Currently, directly sampled endometrial cytology is the most common method of screening for endometrial cancer in Japan. The purpose of this study are as follows: comparison of the detection rate between endometrial cytology and biopsy for diagnosis of endometrial cancers, and comparison of the diagnostic value of conventional and liquid-based preparation for endometrial cytology. Materials & Methods: From 2000 to 2016, a total number of 2,326 patients with endometrial cancer underwent surgery at Cancer Institute Hospital, Tokyo Japan. Among them, we reviewed preoperative cytology and biopsy specimens of 1860 cases. The direct endometrial sampling method was applied for endometrial cytology. Results: The detection rate of endometrial cancers between cytology and biopsy in all stages was 83.9% and 95.7% respectively, and in early stage was 79.4% and 90.0% respectively. There were significant differences between them. Comparison of the two preparation methods (conventional and liquid-based preparation). Even though there were some differences between conventional and liquid-based preparation, our results indicated that both methods are useful for detecting endometrial cancers. Conclusions: Although, there were significant differences between cytology and biopsy in the detection rates of endometrial cancers, compared to the endometrial biopsy, endometrial cytology is easier to insert into the uterine cavity and is less painful. Therefore endometrial cytology has been used as a screening for endometrial cancer in Japan. Even though there were some differences between conventional and liquid-based cytology, our results indicated that both methods are useful for detecting endometrial cancers.

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