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Quality of life in patients with metabolically healthy obesity before and after weight loss

Joint Event on Asia Pacific Conference on Diabetes & Oncology

December 04-05, 2019 | Tokyo, Japan

Tatiana Romantsova, Ostrovskaya E, Gerasimov A and Novoselova T

I.M. Sechenov First Moscow State Medical University, Russia

Posters & Accepted Abstracts: RRJMHS


Obesity has a negative impact on the quality of life indicators; weight loss has a distinct positive effect on these parameters. The purpose of the study was to analyze Quality Of Life (QoL) indicators in patients with Metabolically Healthy Obesity (MHO) associated with ≥5% weight loss. The study involved 44 females with MHO (according to the IDF criteria of the Metabolic Syndrome (MS), 2005) and 33 females with Metabolically Unhealthy Obesity (MUHO) aged 19-59 years. To assess QoL, we used the SF-36 questionnaire (Medical Outcomes Study-Short Form 36). Initially QoL indicators in both groups were not significantly different statistically. The physical component of health (PHsum) in the MHO and MUHO groups averaged 53.9±6.7 and 50.6±6.3 points (p=0.032).The mental component of health (MHsum) averaged 42.1±1.8 and 45.1±1.8 points (p=0.255). The ≥5% decrease in body weight (from the initial body weight) after 6 months led to an increase in the indicators of physical role functioning by 11.6%, vitality by 12.8%, social functioning by 11.2%, emotional role functioning by 11.9%, mental health by 8.8% (p<0.05) in the MHO group, while in the MUHO group the indicators of physical role functioning increased by 24.6%, emotional role functioning by 39.5% and mental health by 9.2% (p<0.05). The MHO group is characterized by higher physical component of health, without a statistically significant difference in the indicators of each of the 8 scales of the SF-36 questionnaire. A≥5% decrease in the body mass in patients of both groups is accompanied by the increase in the indicators of QoL.


Tatiana Romantsova is currently working as a Professor at Department of Endocrinology in Sechenov University, Moscow. He is the author of 215 scientifi c articles.

E-mail: [email protected]