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Pathology 2018
Research & Reviews: Journal of Medical and Health Sciences
ISSN: 2319-9865
Page 46
October 08-09, 2018
Edinburgh, Scotland
17
th
International Conference on
Pathology & Cancer
Epidemiology
A
s per the latest Indian Council of Medical Research Statistics,
breast cancer is the most common cancer among Indian
women with an estimation of 1.5 lakh new cases (over 10% of
all cancers seen during 2016). According to the National Cancer
Registry almost 48% of breast cancer patients currently are below
50 years of age in comparison to 25 years ago, when 69% of the
patients were over 50 years of age. Mammographic screening
has not become a method of cancer prevention in India, partly
because of the cost and also lack of its awareness. Nevertheless,
in urban areas screening sonomammograms and image guided
biopsies of suspicious lesions has led to an increased detection
of early breast cancer. In our study on 146 cases of non-palpable
screen detected biopsy proven early breast cancer, we found that
Luminal A subtype was the most common. It was also seen that
a subset of patients of younger age (<50 years) showed larger
and higher-grade tumours with triple negative and HER2 positive
subtypes. 12% of our patients showed nodal and systemic
metastasis, both of which were seen mostly in the non-Luminal A
sub types. Therewere 33 cases of DCIS and one case ofmalignant
Phyllodes tumour.
Biography
Aishwarya Sitaramhas doneMBBS, MD and DNB from India and completed
Postdoctoral Certificate Course in Oncopathology from P D Hinduja Hospi-
tal &MRC, Mumbai, India. She is currently working as Assistant Professor in
K J Somaiya Medical College and Research Centre, Mumbai, India.
aishwarya.sitaram@gmail.comMolecular sub typing on IHC4 of non-palpable early breast
cancer: a screening population study at Mumbai, India
Aishwarya Sitaram, Anita S Bhaduri, R B Deshpande, Chitra V Madiwale,
Satyakam Sawaimoon
and
Vinay Deshmane
P D Hinduja National Hospital and Medical Research Centre, Mumbai
Aishwarya Sitaram et al., RRJMHS 2018
Volume: 7
Figure 1:
ER and PR expression correlated with tumor grade.
Figure 2:
Comparison of tumor
parameters in two age groups.