e-ISSN: 2321-6182 p-ISSN: 2347-2332
Radhika S. Iyer*
Department of Pharmacognosy and Phytopharmaceutical Sciences, Manipal College of Pharmaceutical
Sciences, Manipal, India
Received: 05-Mar-2025, Manuscript No. jprpc-25-169377; Editor assigned: 7-Mar-2025, Pre-QC No. jprpc-25-169377 (PQ); Reviewed: 18-Mar-2025, QC No jprpc-25-169377; Revised: 25-Mar- 2025, Manuscript No. jprpc-25-169377 (R); Published: 30-Mar-2025, DOI: 10.4172/2347-1234.13.008
Citation: Radhika S. Iyer, Green Extraction Techniques in Herbal Pharmacognosy. J Pharmacogn Phytochem. 2025.13.008.
Copyright: © 2025 Radhika S. Iyer, this is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Green extraction refers to the development of sustainable, efficient, and environmentally friendly methods for isolating bioactive compounds from medicinal plants. With increasing concern over toxic solvents, energy usage, and environmental waste, novel green extraction techniques offer safer alternatives. This article reviews the principles, types, and applications of green extraction methods in herbal pharmacognosy, with emphasis on phytochemical yield, safety, and industrial scalability.
Conventional solvent-based extraction techniques, while effective, often involve high energy consumption, hazardous solvents, and long processing times. Green extraction prioritizes methods that reduce solvent use, energy requirements, and environmental impact while improving yield and preserving thermolabile phytochemicals. These techniques are gaining prominence in the production of herbal extracts, nutraceuticals, and standardized phytopharmaceuticals [1].
Technique |
Description |
Advantages |
Supercritical Fluid Extraction (SFE) |
Uses supercritical COâ?? at high pressure |
Non-toxic, solvent-free, high selectivity |
Microwave-Assisted Extraction (MAE) |
Microwaves heat plant matrix internally |
Fast, high yield, minimal solvent |
Ultrasound-Assisted Extraction (UAE) |
Acoustic cavitation disrupts plant cells |
Energy-efficient, enhances mass transfer |
Pressurized Liquid Extraction (PLE) |
High temp & pressure with water/ethanol |
Accelerates extraction, less solvent |
Enzyme-Assisted Extraction (EAE) |
Uses cellulase, pectinase to break cell walls |
Mild, improves release of actives |
Natural Deep Eutectic Solvents (NADES) |
Biocompatible solvent systems (e.g., cholineâ??glucose) |
Sustainable, tunable for polarity |
Plant |
Target Compound |
Green Method |
Curcuma longa |
Curcumin |
MAE, UAE |
Andrographis paniculata |
Andrographolide |
SFE |
Ginkgo biloba |
Flavonol glycosides |
PLE |
Ocimum sanctum |
Eugenol |
UAE |
Camellia sinensis |
Catechins |
EAE |
Green methods often improve extraction efficiency and preserve compound integrity.
Parameter |
Conventional Solvent Extraction |
Green Extraction |
Solvent Use |
High (often toxic) |
Minimal, safe |
Energy Use |
High |
Moderate to low |
Selectivity |
Broad, non-specific |
Targeted |
Extraction Time |
Long (hours) |
Short (minutes) |
Safety |
Flammable, hazardous |
Eco-friendly |
Scalability |
Established |
Emerging |
Green extraction is revolutionizing the field of herbal pharmacognosy by offering sustainable, efficient, and consumer-safe alternatives to conventional methods. Though challenges remain in cost and scalability, advances in green chemistry and extraction technology are making these methods increasingly accessible to academia, industry, and regulatory bodies.