All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Nanoparticle Synthesis with Co Precipitation

George Stain*

Department of Nutritional Science, Tokyo University of Agriculture, Tokyo, Japan

*Corresponding Author:
George Stain
Department of Nutritional Science,
Tokyo University of Agriculture,

Received: 30-May-2022, Manuscript No. JPN-22- 68520; Editor assigned: 2-Jun-2022, Pre QC No. JPN-22- 68520 (PQ); Reviewed: 16-Jun-2022, QC No. JPN-22- 68520; Revised: 23-Jun- 2022, Manuscript No. JPN-22- 68520 (A); Published: 30-Jun- 2022, DOI: 10.4172/23477857- 3528.10.3.002

Visit for more related articles at Research & Reviews: Journal of Pharmaceutics and Nanotechnology


The term "Nanoparticle synthesis" describes processes for producing nanoparticles. Nanoparticles can be produced by "bottom-up" processes, such as nucleating and growing particles from tiny molecular distributions in liquid or vapour phase, or they can be formed from bigger molecules. Functionalization by conjugation to bioactive compounds is another method of synthesis. Since the very beginning of the development of nano-science, high yield and low cost nanomaterial synthesis has been a major difficulty. The ability to produce nanoparticles with various shapes, mono-dispersities, chemical compositions, and sizes is necessary for their use in medicine.

Co-precipitation is a simple method for synthesising nanoparticles that can be made in a variety of sizes. The production of more uniformly sized nanoparticles has been accomplished using a number of additional techniques. An iron supply and sodium hydroxide nanoemulsion are combined to form magnetite nanoparticles (NaOH). The surfactant is cleaned with ethanol after the nanoparticles have been removed using acetone lysis. Colloidal nanoparticles exhibit significant magnetism and super-paramagnetic characteristics.

The dissolved compounds are present in the oil and water phases. In addition, the system's physicochemical characteristics play a significant role in the choice of surfactant material. This approach works with cationic, anionic, and non-ionic surfactants of any sort. The process of scaling up and the negative impacts of residual surfactants could pose some challenges for nanoparticles made using microemulsion techniques via using a water/oil microemulsion, Chin and Yaacob (2007) demonstrated iron oxide NPs smaller than 10 nm, which are smaller than those produced by coprecipitation. Lee demonstrated in a different investigation that utilising an iron precursor at a high temperature led to the formation of crystalline maghemite nanoparticles. Sun (2004) also found that very tiny magnetite nanoparticles were created in the same way.

There are many ways to create nanoparticles, including physical, chemical, and biological processes. In general, physical and chemical approaches are thought to be the most effective for producing stable, uniform-sized nanoparticles. These methods, however, cost a fortune and let dangerous or harmful substances into the environment. Chemical processes that involve toxic chemicals for nanoparticle synthesis result in nanoparticles that are less acceptable for usage in food, cosmetics, or medicine. Enhancing the biocompatibility of nanoparticles is crucial because many of them have been widely used in medical applications, illness detection, and cosmetics. For the past ten years, biosynthetic methods have received a lot of attention in the quest to produce metal nanoparticles including silver, gold, copper, and platinum.

Because the stabilising and reducing agents utilised in biosynthetic nanoparticle synthesis are bacteria, fungi, yeasts, or plants themselves or their active components, these methods are thought to be environmentally beneficial.

For the green production of different nanoparticles, multiple plant species and materials originating from plants have been discovered over the past ten years. Numerous plants include a variety of biologically active substances that function as reducing agents for metal salts, including alkaloids, phenols, flavonoids, ascorbic acid, citric acid, polyphenols, terpenes, and reductase. These phytosynthesis methods hold great promise because the plant components can function as capping and reducing agents. Synthesis of phytonanoparticles might occur via extracellular or intracellular processes.

The chosen plant species have the ability to produce metallic nanoparticles within their cells when grown in organic media, soil, or hydroponic solutions that are rich in metals. To culture, watch after, track, and harvest nanoparticles needs a lot of work. Additionally, using such techniques results in the adulteration of biomolecules, other components, plant pathogens, and tissues.