Targeted Nanoparticles for Anti-Cancer Drug Delivery: A Review
It is a challenge to eradicate cancer cells while sparing normal cells. Only to improve the biodistribution of cancer drugs, nanoparticles are designed for optimal size and surface characteristics to broaden their circulation time within the blood circulation. They are also able to carry their loaded active drugs to cancer cells by using the unique functional changes of tumors, as like their enhanced permeability and retention effect and the tumor microenvironment. In this review report, we have discussed the current status of nanoparticles developed as targeting delivery systems for anticancer drugs.