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Pure bio-active compounds from the Egyptian fungus Aspergillus ASAI


Joint Event on 4th Pharmaceutical Chemistry Conference & 12th World congress on Future Pharma

June 27-28, 2019 | Amsterdam, Netherlands

Mostafa Alasmaey,Ahmed S Abdel-Razek, Dennis Abatis, Nikolas Fokialakis, Mohamed Shaaban and Aligiannis Nektarios

National and Kapodistrian University of Athens, Greece, Al-Azhar University, Egypt National Research Centre, Egypt

Posters & Accepted Abstracts: Pharmaceutical Analysis

Abstract

The last two decades have shown that the fungi can be ‘bio-factories’ of bioactive secondary metabolites with novel skeletons. Amongst the fungi Aspergillus species are a rich source of structurally unique and biologically active secondary metabolites. During the course of our investigation on bioactive natural products from micro-organisms, we found the extract of fungus ASAI was obtained from the soil sample collected at Giza province, Egypt and identified as Aspergillus sp., it had a promising activity against many pathogenic test organisms. Chromatographic techniques isolation led to the isolation of nine pure compounds, which identified by using 1D and 2D NMR and classified into three types: triterpene, quinone and diketopiperazine alkaloid.

Biography

Mostafa Alasmaey has completed his BSc in Organic Chemistry and MSc in Natural Product Chemistry from Faculty of Science, Al-Azhar University, Egypt, and he is working as a Lecturer Assistant in the same department from 2012. He is pursuing his PhD at Pharmacy School, National and Kapodistrian University of Athens, Greece. He has published two papers in reputed journals in the field of Natural Product Chemistry.

E-mail: m167alasmae@yahoo.com