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ISSN: 2322-0066

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Cancer systems biology encompasses the application of systems biology approaches to cancer research, in order to study the disease as a complex adaptive system with emerging properties at multiple biological scales. More explicitly, because cancer spans multiple biological, spatial and temporal scales, communication and feedback mechanisms across the scales create a highly complex dynamic system. The relationship between scales is not simple or necessarily direct, and sometimes become combinatorial, so that systems approaches are essential to evaluate these relationships quantitatively and qualitatively.

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Seminars in Cancer Biology, Cancer Biology and Therapy, Cancer Biology and Medicine

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